Duke Surgery Holds 3rd Annual Research Day

The Department of Surgery held its 3rd Annual Research Day April 25. The department holds this event annually to advance its mission of improving patient care through research and training the next generation of surgeon-scientists. The event recognizes the accomplishments of fellows, residents, and students engaged in clinical or basic and translational research through the department. This year, over 90 abstracts were submitted by faculty and trainees for oral and poster presentations.

Ronald J. Weigel, MD, PhD, MBA, EA Crowell Jr. Professor and Chair of Surgery at the University of Iowa Carver College of Medicine, served as guest judge and gave the inaugural Hunter McGuire Sweaney Lectureship in Surgery. Through his estate, Dr. Hunter Sweaney endowed a fund to establish the lectureship to be shared by both the Duke University School of Medicine and the University of North Carolina School of Medicine. Dr. Weigel presented on “The Biological Basis of Modern Surgical Practice.”

Congratulations to this year’s winners! We look to forward to another successful event next year.



Basic Science

Implantable Oxygen Platform for Continuous, Real-Time Detection of Vascular Perfusion and Ischemia

Mohamed Ibrahim, MD
Ryan Schweller, PhD, Mahmoud Mohamed, David Powers MD, DMD, Bruce Klitzman, PhD

Ibrahim Research Day
From left: Dr. Ranjan Sudan, Vice Chair of Education; Dr. Ronald J. Weigel, Guest Judge; Dr. Mohamed Ibrahim, Basic Science Winner; and Dr. Allan Kirk, Chair of Surgery

Clinical Research

Just a Nudge: Applying Behavioral Incentives to Engage Residents in Quality Improvement Education

Ashley Wietsma, MD
Eugene Cone, MD, Johnathan Bergman, Tannaz Moin, Arlene Fink, Jonathan Routh, MD, MPH, B. Price Kerfoot, MD, Charles Scales Jr., MD

From left: Dr. Ranjan Sudan, Vice Chair of Education; Dr. Ronald J. Weigel, Guest Judge; Dr. Ashley Wietsma, Clinical Research Winner; and Dr. Allan Kirk, Chair of Surgery


Podium Presentations

Basic Science

Cosette DeChant

S1P1 Loss Mediates Bone Marrow T-Cell Sequestration in the Setting of Intracranial Tumors

Cosette DeChant
Pakawat Chongsathidkiet, Karolina Woroniecka, Hanna Kemeny, Kristen Rhodin, Xiuyu Cui, Peter Fecci, MD, PhD


Mohamed Ibrahim, MD

Implantable Oxygen Platform for Continuous, Real-time Detection of Vascular Perfusion and Ischemia

Mohamed Ibrahim, MD
Ryan Schweller, PhD, Mahmoud Mohammed, David Powers, MD, DMD, Bruce Klitzman, PhD

Michael Mulvihill, MD

Rhesus-Specific Anti-Thymocyte Globulin as an Adjuvant to Costimulatory Blockade-Based Immunotherapy

Michael Mulvihill, MD
Brian Ezekian, MD, Qimeng Gao, Kannan Samy, MD, Robert Davis, MD, PhD, Frank Leopardi, Aaron Belli, W. Flores, Adam Buzby, MBA, Keith Reimann, DVM, Brad Collins, MD, Allan Kirk, MD, PhD, FACS

Kristen Rhodin

Targeting Immunostimulatory Pathways in Combination with Multi-Checkpoint Blockade Improves Survival in Intracranial Neoplasms

Kristen Rhodin
Karolina Woroniecka, Pakawat Chongsathidkiet, Xiuyu Ciu, Hanna Kemeny, Cosette Dechant, Peter Fecci, MD, PhD

Ruya Zhao

Tumor Microenvironment in CRISPR: Cas9-Mediated BRCA1 Knockdown Adipose Stem Cell Model

Ruya Zhao
Rayan Kaakati; Xingjian Liu, PhD, Fang Li, PhD, Andrew Lee, Robin Bachelder, PhD, Chuan-Yuan Li, PhD; Scott Hollenbeck, MD


Clinical Research

Brittany Campbell

Patient Preferences for DCIS Treatment Strategies: A Discrete-Choice Experiment

Brittany Campbell
Jui-Chen Yang, MEM; Juan Marcos Gonzalez, PhD; Shelby Reed, PhD; Laura Havrilesky, MD, MHSc; F. Reed Johnson, PhD; Shelley Hwang, MD, MPH

Amanda Nash


Pumping Donor Kidneys Reduces Delayed Graft Function and Improves Allograft Survival

Amanda Nash
Mariya L. Samoylova, MD, Todd Brennan, MD, MS



Banafsheh Sharif Askary
Banafsheh Sharif-Askary

Geospatial Econometric Exploration of Risk Factors for Loss to Followup in Cleft Care

Banafsheh Sharif-Askary
Peter Bittar, Alfredo Farjat, PhD, Beiyu Liu, PhD, Joao Vissoci, PhD, Alexander Allori, MD



Nina Tamirisa, MD

Axillary Nodal Evaluation in Elderly Breast Cancer Patients: Potential Effects on Treatment Decisions and Survival

Nina Tamirisa, MD
Samantha Thomas, MS, Lola Fayanju, MD, MA, MPHS, Rachel Greenup, MD, MPH, Laura Rosenberger, MD, Terry Hyslop, PhD, Shelley Hwang, MD, MPH, Jennifer Plichta, MD, MS



Ashley Wietsma, MD

Just a Nudge: Applying Behavioral Incentives to Engage Residents in Quality Improvement Education

Ashley Wietsma, MD
Eugene Cone, MD, Jonathan Bergman, Tannaz Moin, Arlene Fink, Jonathan Routh, MD, MPH, B. Price Kerfoot, MD, Charles Scales Jr., MD


Posters of Distinction


Basic Science & Translational Research

Synovium Production of Kynurenine in Arthritic Knee Joints: Implications for Treating Comorbid Pain and Depression in Osteoarthritis

Angel (Fangyu) Chen, Nicholas Allen, Ivan Spasojevic, PhD, Michael Bolognesi, MD, Samuel Adams Jr., MD

Immune Pathway Dysregulations in Inflammatory Breast Cancer: Implications in Cancer Health Disparity

Whitney Lane, MD, Steven Van Laere, PhD, Gayathri Devi, PhD

Targeting the DNA Synthesis Pathway with a Novel RR Inhibitor in Breast Cancer

Pranalee Patel, Gayathri Devi, PhD, Renzhi Zhan, Ben Mirman

Pharmacological Inhibition of the NLRP3 Inflammasome Prevents Bladder Decompensation in a Rat Model of Chronic Bladder Outlet Obstruction

Stephanie Sexton, MD, Francis Hughes Jr., PhD, Patrick Leidig, MD, Huixia Jin, Todd Purves, MD, PhD

Poster collage


Clinical Research

Analgesic Prescribing Patterns for Acute Symptomatic Urinary Stones in US Emergency Departments

Leonid Aksenov, Ashley Wietsma, MD, Michael Lipkin, MD, Jonathan Routh, MD, MPH, Glenn Preminger, MD, Charles Scales Jr., MD

Parental Preferences for the Treatment of Vesico-Ureteral Reflux: A Best-Worst Scaling Analysis

Zachary Dionise, Glenn Preminger, MD, Michael Lipkin, MD

Unexpected Cardiac MRI Findings in Patients Presenting to the Emergency Department for Possible Acute Coronary Syndrome

David Painter, MD, Cole Ziegler, Joseph Borawski, MD, Raymond Kim, MD, Han Kim, MD, Alexander Limkakeng Jr., MD, MHS

Significant Delay in Adjuvant Chemotherapy Still Confers a Survival Advantage in Stage III Colon Cancer

Megan Turner, MD, Norma Farrow, MD, Kristen Rhodin, Zhifei Sun, MD, Mohamed Adam, MD, Christopher Mantyh, MD, FACS, John Migaly, MD, FACS

Return to Operating Room Outcomes after Free Flap Reconstruction

Ruya Zhao, Matthew Lyes, Scott Hollenbeck, MD


Quick Shot Presentations

Justin Pollara, PhD

Innate Immune Activation in Deceased Organ Donors

Justin Pollara, PhD
Assistant Professor of Surgery
Division of Surgical Sciences




Lola Fayanju, MD, MPHS

Patient-Reported Distress in Breast Cancer Patients: A Tool to Improve Care and Reduce Disparities

Oluwadamilola “Lola” Fayanju, MD, MA, MPHS
Assistant Professor of Surgery
Division of Surgical Oncology



Justin Broder, MD

Engineering New Imaging Technologies

Joshua Broder, MD
Associate Professor of Surgery
Division of Emergency Medicine




Jonathan Routh, MD, MPH

Improving Care for Newborns with Spina Bifida in the United States

Jonathan Routh, MD, MPH
Paul H. Sherman, MD, Associate Professor of Surgery
Division of Urology