Skip to main content

Debara Lyn Tucci, MD

Adjunct Professor in the Department of Head and Neck Surgery & Communication Sciences
Office: 1559 Hosp South, Blue Zone, Durham, NC 27710
Campus Mail: DUMC Box 3805 Med Ctr, Durham, NC 27710

The focus of current research efforts is in defining the effects of conductive hearing impairment on the development and function of the central auditory system. The ultimate goal of this research is to understand the impact of hearing loss, such as that associated with otitis media, on the development of auditory function in children. Experiments are currently being performed in which central auditory system activity is studied using the 2-deoxyglucose method following unilateral neonatal conductive hearing loss. Future experiments will examine changes in cell structure and interneuronal connections following acute and chronic conductive hearing loss in both neonatal and adult animals.

A second research program is focused on issues related to the cochlear implant. The cochlear implant is a device which allows for electrical stimulation of the auditory nerve in profoundly deaf patients. It has previously been demonstrated in animal studies as well as in human tissue histopathology that degeneration of central auditory pathways occurs following severe damage to the inner ear. It has been suggested that the introduction of electrical stimulation via a cochlear implant may prevent or reverse some of these degenerative changes. Experiments conducted previously examined this issue in the neonatally and adult deafened rat. Tissue analysis is currently undergoing completion.

Education and Training

  • M.D., University of Virginia, 1985

Publications

Stachler, Robert J., Sujana S. Chandrasekhar, Sanford M. Archer, Richard M. Rosenfeld, Seth R. Schwartz, David M. Barrs, Steven R. Brown, et al. “Clinical practice guideline: sudden hearing loss.” Otolaryngol Head Neck Surg 146, no. 3 Suppl (March 2012): S1-35. https://doi.org/10.1177/0194599812436449.

Full Text

Witsell, D. L., D. L. Tucci, and K. Schulz. “Response to "a call for systematic data collection in tinnitus patients," from Michael landgrebe and berthold langguth.” Otolaryngol Head Neck Surg, February 2012. https://doi.org/10.1177/0194599811430044.

Full Text

Witsell, David L., Kristine A. Schulz, Kathy Moore, Debara L. Tucci, and Debara L. CHEER Investigators. “Implementation and testing of research infrastructure for practice-based research in hearing and communication disorders.” Otolaryngol Head Neck Surg 145, no. 4 (October 2011): 565–71. https://doi.org/10.1177/0194599811406369.

Full Text

Witsell, David L., Steven D. Rauch, Debara L. Tucci, Steven A. Telian, Peter S. Roland, Anh T. Nguyen-Huynh, and Kristine Schulz. “The Otology Data Collection project: report from the CHEER network.” Otolaryngol Head Neck Surg 145, no. 4 (October 2011): 572–80. https://doi.org/10.1177/0194599811416063.

Full Text

Wilson, Blake S., Michael F. Dorman, Marty G. Woldorff, and Debara L. Tucci. “Cochlear implants matching the prosthesis to the brain and facilitating desired plastic changes in brain function.” Prog Brain Res 194 (2011): 117–29. https://doi.org/10.1016/B978-0-444-53815-4.00012-1.

Full Text

Schellenberg, Kerri, Richard Bedlack, and Debara Tucci. “Roaring in the ears: patulous Eustachian tube in bulbar amyotrophic lateral sclerosis.” Amyotroph Lateral Scler 11, no. 4 (August 2010): 395–96. https://doi.org/10.3109/17482960903501931.

Full Text

Aliabadi, Hamidreza, James J. Vredenburgh, Richard G. Everson, Annick Desjardins, Henry S. Friedman, Roger E. McLendon, Debara L. Tucci, and John H. Sampson. “Bevacizumab fails to treat temporal paraganglioma: discussion and case illustration.” J Neurooncol 98, no. 3 (July 2010): 427–30. https://doi.org/10.1007/s11060-009-0091-2.

Full Text

Pages